Adenosine-guanosine interactions in the isolated dog atrium.
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Electrochemical and Spectroscopic Studies of Interactions of Mn(III) Complexes with Nucleic Bases and Nucleosides
The complexes of Mn(OAc)3 and/or Mn(acac)3 with nucleic bases and nucleosides (adenine, guanine, xanthine, adenosine and guanosine) have been synthesized in nonaqueous solution. Polarographic and spectroscopic (IR and Visible) methods have been used to establish the active site(s) on the imidazole and pyrimidine rings in the nucleic bases and nucleosides for the intera...
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CHIBA, S. Potentiation of the Negative Chronotropic and Isotropic Effects of Adenosine by Dipyridamole. Tohoku J. exp. Med ., 1974, 114 (1), 45-48 The isolated right atrium of the dog was perfused with blood led from a support dog. The selective injection of dipyridamole into the sinus node artery at a dose of 1-10 ƒÊg induced a slight negative chronotropic and positive inotropic effect. The ad...
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Background: Adenosine receptors play an important role in the treatment of paroxysmal supraventricular tachycardia in cardiovascular system. This effect is through interaction with A1 type of G-protein-coupled adenosine receptors. The effect of N6-cyclopentyladenosine (CPA), an A1-selective adenosine agonist, was studied on ouabain-induced toxicity in spontaneously beating isolated guinea pig a...
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عنوان ژورنال:
- Japanese journal of pharmacology
دوره 30 1 شماره
صفحات -
تاریخ انتشار 1980